Searchable abstracts of presentations at key conferences in endocrinology

ea0046p8 | (1) | UKINETS2016

Blood measurement of neuroendocrine gene transcripts defines the effectiveness of operative resection and ablation strategies

Modlin Irvin M , Frilling Andrea , Salem Ronald R , Alaimo Daniele , Drymousis Panagiotis , Wasan Harpreet S , Callahan Stephen , Faiz Omar , Weng Lei , Teixeira Nancy , Bodei Lisa , Drozdov Ignat , Kidd Mark

Background: Surgery is the only curative treatment for gastroenteropancreatic neuroendocrine tumors (GEP-NETs), but the prediction of residual disease/recurrence is limited in the absence of optimal biomarkers. We examined whether a blood-based multianalyte neuroendocrine gene transcript assay (NETest) would define tumor cytoreduction and therapeutic efficacy.Methods: The NETest is a polymerase chain reaction–based analysis of 51 genes. Disease acti...